منابع مشابه
2-Amino-4-methyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carbonitrile
In the title compound, C(10)H(12)N(2)S, the thio-phene ring is essentially planar (r.m.s. deviation = 0.0290 Å). The two C atoms of the cyclo-hexene ring (at positions 6 and 7) are disordered over two sets of sites in a 0.810 (5):0.190 (5) ratio. The cyclo-hexene rings in both the major and minor occupancy conformers adopt a half-chair conformation. In the crystal, there are two types of N-H⋯N ...
متن کاملCrystal structure of rac-2,3-diphenyl-2,3,5,6-tetrahydro-4H-1,3-thiazin-4-one 1-oxide
In the title compound, C16H15NO2S [alternative name: rac-2,3-diphenyl-1,3-thia-zinan-4-one 1-oxide], the thia-zine ring exhibits an envelope conformation, with the S atom forming the flap. The sulfoxide O atom is in a pseudo-axial position on the thia-zine ring and is trans to the phenyl group on C-2. The phenyl rings form a dihedral angle of 89.47 (19)°. In this racemate crystal, homochiral mo...
متن کاملQuantitative determination of the urinary cortisol metabolites, tetrahydro F, allo-tetrahydro F and tetrahydro E: effects of adrenocorticotropin and complex trauma in the human.
Methods for the quantitative estimation of plasma cortisol concentration have been devised by Nelson and Samuels (1), Silber and Porter (2), and Peterson and Wyngaarden (3) who used the sulfuric acid-induced fluorescence developed by Sweat (4). Together with urinary procedures (5, 6) these techniques have been employed to determine the secretion of cortisol by the adrenal in normal and patholog...
متن کاملDisposition and Metabolism of 1-(Tetrahydro-2-furanyl)-5-fluorouracil (Ftorafur) in Humans1
The pharmacology of high-dose 1-(tetrahydro-2-furanyl)5-fluorouracil (FT) has been studied by radiochemical and Chromatographie techniques in eight patients. Plasma disappearance of FT was exponential, with a half-life of 8.8 hr. Plasma concentrations of 5-fluorouracil (FUra) were sustained at 12.8 nmol/ml (1.7 /¿g/ml) for at least 48 hr after FT administration. The concentrations of FUra deri...
متن کاملSynthesis of novel mast cell-stabilising and anti-allergic 1,2,3,4-tetrahydro-1-naphthalenols and related compounds.
In a continuation of our studies into indan and tetralin systems as novel modulators of allergic and inflammatory phenomena, we have extended our work to include dimers linked via C-C bonds. Of these compounds, 2-Benzyl-2-[2-phenyl-1-ethenyl]-1,2,3,4-tetrahydro-1-naphthalenol 12 exhibited most promising activity both in vitro and in vivo.
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ژورنال
عنوان ژورنال: Berichte der deutschen chemischen Gesellschaft
سال: 1910
ISSN: 0365-9496,1099-0682
DOI: 10.1002/cber.191004303117